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ProteinShader is a molecular visualization tool that can produce illustrative renderings of proteins that approximate what an artist might create using pen and ink. This free platform-independent program is written in Java and OpenGL Shading Language.
avoCADo is a 3D design and modeling program (CAD) which aims to be a collaborative tool with an intuitive user interface for both engineers and artists alike. avoCADo is open source under the GPL.