Compare the Top Large Language Models that integrate with Python as of April 2026 - Page 4

This a list of Large Language Models that integrate with Python. Use the filters on the left to add additional filters for products that have integrations with Python. View the products that work with Python in the table below.

  • 1
    Gemini 2.5 Flash
    Gemini 2.5 Flash is a powerful, low-latency AI model introduced by Google on Vertex AI, designed for high-volume applications where speed and cost-efficiency are key. It delivers optimized performance for use cases like customer service, virtual assistants, and real-time data processing. With its dynamic reasoning capabilities, Gemini 2.5 Flash automatically adjusts processing time based on query complexity, offering granular control over the balance between speed, accuracy, and cost. It is ideal for businesses needing scalable AI solutions that maintain quality and efficiency.
  • 2
    Gemini 2.5 Flash-Lite
    Gemini 2.5 is Google DeepMind’s latest generation AI model family, designed to deliver advanced reasoning and native multimodality with a long context window. It improves performance and accuracy by reasoning through its thoughts before responding. The model offers different versions tailored for complex coding tasks, fast everyday performance, and cost-efficient high-volume workloads. Gemini 2.5 supports multiple data types including text, images, video, audio, and PDFs, enabling versatile AI applications. It features adaptive thinking budgets and fine-grained control for developers to balance cost and output quality. Available via Google AI Studio and Gemini API, Gemini 2.5 powers next-generation AI experiences.
  • 3
    Grok 4 Heavy
    Grok 4 Heavy is the most powerful AI model offered by xAI, designed as a multi-agent system to deliver cutting-edge reasoning and intelligence. Built on the Colossus supercomputer, it achieves a 50% score on the challenging HLE benchmark, outperforming many competitors. This advanced model supports multimodal inputs including text and images, with plans to add video capabilities. Grok 4 Heavy targets power users such as developers, researchers, and technical enthusiasts who require top-tier AI performance. Access is provided through the premium “SuperGrok Heavy” subscription priced at $300 per month. xAI has enhanced moderation and removed problematic system prompts to ensure responsible and ethical AI use.
  • 4
    Claude Opus 4.1
    Claude Opus 4.1 is an incremental upgrade to Claude Opus 4 that boosts coding, agentic reasoning, and data-analysis performance without changing deployment complexity. It raises coding accuracy to 74.5 percent on SWE-bench Verified and sharpens in-depth research and detailed tracking for agentic search tasks. GitHub reports notable gains in multi-file code refactoring, while Rakuten Group highlights its precision in pinpointing exact corrections within large codebases without introducing bugs. Independent benchmarks show about a one-standard-deviation improvement on junior developer tests compared to Opus 4, mirroring major leaps seen in prior Claude releases. Opus 4.1 is available now to paid Claude users, in Claude Code, and via the Anthropic API (model ID claude-opus-4-1-20250805), as well as through Amazon Bedrock and Google Cloud Vertex AI, and integrates seamlessly into existing workflows with no additional setup beyond selecting the new model.
  • 5
    GPT-5 pro
    GPT-5 Pro is OpenAI’s most advanced AI model, designed to tackle the most complex and challenging tasks with extended reasoning capabilities. It builds on GPT-5’s unified architecture, using scaled, efficient parallel compute to provide highly comprehensive and accurate responses. GPT-5 Pro achieves state-of-the-art performance on difficult benchmarks like GPQA, excelling in areas such as health, science, math, and coding. It makes significantly fewer errors than earlier models and delivers responses that experts find more relevant and useful. The model automatically balances quick answers and deep thinking, allowing users to get expert-level insights efficiently. GPT-5 Pro is available to Pro subscribers and powers some of the most demanding applications requiring advanced intelligence.
  • 6
    GPT-5 thinking
    GPT-5 Thinking is the deeper reasoning mode within the GPT-5 unified AI system, designed to tackle complex, open-ended problems that require extended cognitive effort. It works alongside the faster GPT-5 model, dynamically engaging when queries demand more detailed analysis and thoughtful responses. This mode significantly reduces hallucinations and improves factual accuracy, producing more reliable answers on challenging topics like science, math, coding, and health. GPT-5 Thinking is also better at recognizing its own limitations, communicating clearly when tasks are impossible or underspecified. It incorporates advanced safety features to minimize harmful outputs and provide nuanced, helpful answers even in ambiguous or sensitive contexts. Available to all users, it helps bring expert-level intelligence to everyday and advanced use cases alike.
  • 7
    Claude Sonnet 4.5
    Claude Sonnet 4.5 is Anthropic’s latest frontier model, designed to excel in long-horizon coding, agentic workflows, and intensive computer use while maintaining safety and alignment. It achieves state-of-the-art performance on the SWE-bench Verified benchmark (for software engineering) and leads on OSWorld (a computer use benchmark), with the ability to sustain focus over 30 hours on complex, multi-step tasks. The model introduces improvements in tool handling, memory management, and context processing, enabling more sophisticated reasoning, better domain understanding (from finance and law to STEM), and deeper code comprehension. It supports context editing and memory tools to sustain long conversations or multi-agent tasks, and allows code execution and file creation within Claude apps. Sonnet 4.5 is deployed at AI Safety Level 3 (ASL-3), with classifiers protecting against inputs or outputs tied to risky domains, and includes mitigations against prompt injection.
  • 8
    GPT-5.1 Instant
    GPT-5.1 Instant is a high-performance AI model designed for everyday users that combines speed, responsiveness, and improved conversational warmth. The model uses adaptive reasoning to instantly select how much computation is required for a task, allowing it to deliver fast answers without sacrificing understanding. It emphasizes stronger instruction-following, enabling users to give precise directions and expect consistent compliance. The model also introduces richer personality controls so chat tone can be set to Default, Friendly, Professional, Candid, Quirky, or Efficient, with experiments in deeper voice modulation. Its core value is to make interactions feel more natural and less robotic while preserving high intelligence across writing, coding, analysis, and reasoning. GPT-5.1 Instant routes user requests automatically from the base interface, with the system choosing whether this variant or the deeper “Thinking” model is applied.
  • 9
    GPT-5.1 Thinking
    GPT-5.1 Thinking is the advanced reasoning model variant in the GPT-5.1 series, designed to more precisely allocate “thinking time” based on prompt complexity, responding faster to simpler requests and spending more effort on difficult problems. On a representative task distribution, it is roughly twice as fast on the fastest tasks and twice as slow on the slowest compared with its predecessor. Its responses are crafted to be clearer, with less jargon and fewer undefined terms, making deep analytical work more accessible and understandable. The model dynamically adjusts its reasoning depth, achieving a better balance between speed and thoroughness, particularly when dealing with technical concepts or multi-step questions. By combining high reasoning capacity with improved clarity, GPT-5.1 Thinking offers a powerful tool for tackling complex tasks, such as detailed analysis, coding, research, or technical explanations, while reducing unnecessary latency for routine queries.
  • 10
    Gemini 3 Deep Think
    The most advanced model from Google DeepMind, Gemini 3, sets a new bar for model intelligence by delivering state-of-the-art reasoning and multimodal understanding across text, image, and video. It surpasses its predecessor on key AI benchmarks and excels at deeper problems such as scientific reasoning, complex coding, spatial logic, and visual-/video-based understanding. The new “Deep Think” mode pushes the boundaries even further, offering enhanced reasoning for very challenging tasks, outperforming Gemini 3 Pro on benchmarks like Humanity’s Last Exam and ARC-AGI. Gemini 3 is now available across Google’s ecosystem, enabling users to learn, build, and plan at new levels of sophistication. With context windows up to one million tokens, more granular media-processing options, and specialized configurations for tool use, the model brings better precision, depth, and flexibility for real-world workflows.
  • 11
    Claude Opus 4.5
    Claude Opus 4.5 is Anthropic’s newest flagship model, delivering major improvements in reasoning, coding, agentic workflows, and real-world problem solving. It outperforms previous models and leading competitors on benchmarks such as SWE-bench, multilingual coding tests, and advanced agent evaluations. Opus 4.5 also introduces stronger safety features, including significantly higher resistance to prompt injection and improved alignment across sensitive tasks. Developers gain new controls through the Claude API—like effort parameters, context compaction, and advanced tool use—allowing for more efficient, longer-running agentic workflows. Product updates across Claude, Claude Code, the Chrome extension, and Excel integrations expand how users interact with the model for software engineering, research, and everyday productivity. Overall, Claude Opus 4.5 marks a substantial step forward in capability, reliability, and usability for developers, enterprises, and end users.
  • 12
    GPT-5.2

    GPT-5.2

    OpenAI

    GPT-5.2 is the newest evolution in the GPT-5 series, engineered to deliver even greater intelligence, adaptability, and conversational depth. This release introduces enhanced model variants that refine how ChatGPT reasons, communicates, and responds to complex user intent. GPT-5.2 Instant remains the primary, high-usage model—now faster, more context-aware, and more precise in following instructions. GPT-5.2 Thinking takes advanced reasoning further, offering clearer step-by-step logic, improved consistency on multi-stage problems, and more efficient handling of long or intricate tasks. The system automatically routes each query to the most suitable variant, ensuring optimal performance without requiring user selection. Beyond raw intelligence gains, GPT-5.2 emphasizes more natural dialogue flow, stronger intent alignment, and a smoother, more humanlike communication style.
  • 13
    Grok 4.1 Thinking
    Grok 4.1 Thinking is xAI’s advanced reasoning-focused AI model designed for deeper analysis, reflection, and structured problem-solving. It uses explicit thinking tokens to reason through complex prompts before delivering a response, resulting in more accurate and context-aware outputs. The model excels in tasks that require multi-step logic, nuanced understanding, and thoughtful explanations. Grok 4.1 Thinking demonstrates a strong, coherent personality while maintaining analytical rigor and reliability. It has achieved the top overall ranking on the LMArena Text Leaderboard, reflecting strong human preference in blind evaluations. The model also shows leading performance in emotional intelligence and creative reasoning benchmarks. Grok 4.1 Thinking is built for users who value clarity, depth, and defensible reasoning in AI interactions.
  • 14
    Gemini 3.1 Pro
    Gemini 3.1 Pro is Google’s upgraded core intelligence model designed for complex tasks that require advanced reasoning. Building on the Gemini 3 series, it delivers significant improvements in problem-solving performance and logical pattern recognition. On the ARC-AGI-2 benchmark, Gemini 3.1 Pro achieved a verified score of 77.1%, more than doubling the reasoning performance of Gemini 3 Pro. The model is engineered for challenges where simple answers are insufficient, enabling deeper analysis, synthesis, and creative output. It can generate practical outputs such as animated, website-ready SVGs directly from text prompts, combining intelligence with real-world usability. Gemini 3.1 Pro is rolling out in preview across consumer, developer, and enterprise platforms including the Gemini app, NotebookLM, Gemini API, Vertex AI, and Android Studio. With expanded access for Google AI Pro and Ultra users, 3.1 Pro sets a stronger baseline for ambitious agentic workflow & advanced applications.
  • 15
    Gemini 3.1 Flash-Lite
    Gemini 3.1 Flash-Lite is Google’s fastest and most cost-efficient model in the Gemini 3 series, designed for high-volume developer workloads. It delivers strong performance at scale while maintaining affordability, with pricing set at $0.25 per million input tokens and $1.50 per million output tokens. The model significantly improves speed, offering a 2.5x faster time to first answer token and a 45% increase in output speed compared to Gemini 2.5 Flash. Despite its lower cost tier, it achieves high benchmark results, including an Elo score of 1432 and strong performance across reasoning and multimodal evaluations. Gemini 3.1 Flash-Lite supports adaptive “thinking levels,” allowing developers to control how much reasoning power is used for different tasks. It is suitable for large-scale applications such as translation, content moderation, user interface generation, and simulation building.
  • 16
    GPT-5.3 Instant
    GPT-5.3 Instant is an updated version of ChatGPT’s most-used model, designed to make everyday conversations more fluid, helpful, and accurate. The release focuses on improving tone, relevance, and conversational flow based directly on user feedback. It reduces unnecessary refusals and cuts back on overly cautious disclaimers, delivering clearer and more direct answers when appropriate. The model also improves how it integrates web results, providing better-contextualized information rather than long lists of loosely connected links. Accuracy has been strengthened, with measurable reductions in hallucinations across both high-stakes domains and everyday queries. GPT-5.3 Instant enhances creative writing capabilities, producing more textured, emotionally resonant prose. It is available to all ChatGPT users and developers via the API under ‘gpt-5.3-chat-latest,’ with legacy versions scheduled for retirement.
  • 17
    GPT-5.4 Pro
    GPT-5.4 Pro is an advanced AI model developed by OpenAI to deliver high-performance capabilities for professional and complex tasks. It combines improvements in reasoning, coding, and agent-based workflows into a single unified system. The model is designed to work efficiently across professional tools such as spreadsheets, presentations, documents, and development environments. GPT-5.4 Pro also includes native computer-use capabilities, enabling AI agents to interact with software, websites, and operating systems to complete tasks. With support for up to one million tokens of context, it can manage long workflows and large datasets more effectively than previous models. The model also improves tool usage, allowing it to search for and select the right tools during multi-step processes. By delivering more accurate outputs with fewer tokens, GPT-5.4 Pro helps professionals complete complex work faster and more efficiently.
  • 18
    GPT‑5.4 Thinking
    GPT-5.4 Thinking is an advanced reasoning-focused AI model available within ChatGPT, designed to help users complete complex professional tasks more effectively. It combines improvements in reasoning, coding, and agent-based workflows to provide more accurate and reliable outputs. The model can present an upfront outline of its reasoning process, allowing users to adjust instructions while it is generating a response. This capability helps produce results that better align with user goals without requiring multiple follow-up prompts. GPT-5.4 Thinking also improves deep web research, enabling it to locate and synthesize information from multiple sources more efficiently. With stronger context management, it can handle longer conversations and complex problem-solving tasks with greater coherence. These capabilities make GPT-5.4 Thinking well suited for professional knowledge work and advanced analytical tasks.
  • 19
    GPT-5.4 mini
    GPT-5.4 mini is a fast and efficient AI model designed for high-performance tasks such as coding, reasoning, and multimodal understanding. It delivers strong capabilities similar to larger models while maintaining lower latency and cost. The model is optimized for responsive applications where speed is critical, including coding assistants and real-time workflows. GPT-5.4 mini supports advanced features such as tool use, function calling, and image interpretation. It performs well on complex tasks while running significantly faster than previous mini models. The model is also suitable for subagent systems, where it handles smaller tasks within larger AI workflows. By combining speed, efficiency, and strong performance, GPT-5.4 mini enables scalable AI applications across various use cases.
  • 20
    GPT-5.4 nano
    GPT-5.4 nano is a lightweight and highly efficient AI model designed for fast, cost-effective task execution. It is optimized for simple and high-volume tasks such as classification, data extraction, and basic coding support. The model delivers quick responses with minimal latency, making it ideal for real-time and large-scale applications. GPT-5.4 nano improves significantly over previous nano models in both performance and efficiency. It supports essential capabilities like tool use and structured data processing. The model is commonly used as a supporting component within larger AI systems. By focusing on speed and affordability, GPT-5.4 nano enables scalable automation across various workflows.
  • 21
    CodeGemma
    CodeGemma is a collection of powerful, lightweight models that can perform a variety of coding tasks like fill-in-the-middle code completion, code generation, natural language understanding, mathematical reasoning, and instruction following. CodeGemma has 3 model variants, a 7B pre-trained variant that specializes in code completion and generation from code prefixes and/or suffixes, a 7B instruction-tuned variant for natural language-to-code chat and instruction following; and a state-of-the-art 2B pre-trained variant that provides up to 2x faster code completion. Complete lines, and functions, and even generate entire blocks of code, whether you're working locally or using Google Cloud resources. Trained on 500 billion tokens of primarily English language data from web documents, mathematics, and code, CodeGemma models generate code that's not only more syntactically correct but also semantically meaningful, reducing errors and debugging time.
  • 22
    Grok 4 Fast
    Grok 4 Fast is the latest AI model from xAI, engineered to deliver rapid and efficient query processing. It improves upon earlier versions with faster response times, lower latency, and higher accuracy across a variety of topics. With enhanced natural language understanding, the model excels in both casual conversation and complex problem-solving. A key feature is its real-time data analysis capability, ensuring users receive up-to-date insights when needed. Grok 4 Fast is accessible across multiple platforms, including Grok, X, and mobile apps for iOS and Android. By combining speed, reliability, and scalability, it offers an ideal solution for anyone seeking instant, intelligent answers.
  • 23
    Grok 4.1
    Grok 4.1 is an advanced AI model developed by Elon Musk’s xAI, designed to push the limits of reasoning and natural language understanding. Built on the powerful Colossus supercomputer, it processes multimodal inputs including text and images, with upcoming support for video. The model delivers exceptional accuracy in scientific, technical, and linguistic tasks. Its architecture enables complex reasoning and nuanced response generation that rivals the best AI systems in the world. Enhanced moderation ensures more responsible and unbiased outputs than earlier versions. Grok 4.1 is a breakthrough in creating AI that can think, interpret, and respond more like a human.
  • 24
    Claude Sonnet 4.6
    Claude Sonnet 4.6 is Anthropic’s most advanced Sonnet model to date, delivering significant upgrades across coding, computer use, long-context reasoning, agent planning, and knowledge work. It introduces a 1 million token context window in beta, allowing users to analyze entire codebases, lengthy contracts, or large research collections in a single session. The model demonstrates major improvements in instruction following, consistency, and reduced hallucinations compared to previous Sonnet versions. In developer testing, users strongly preferred Sonnet 4.6 over Sonnet 4.5 and even favored it over Opus 4.5 in many coding scenarios. Its enhanced computer-use capabilities enable it to interact with real software interfaces similarly to a human, improving automation for legacy systems without APIs. Sonnet 4.6 also performs strongly on major benchmarks, approaching Opus-level intelligence at a more accessible price point.
  • 25
    GPT-5.4

    GPT-5.4

    OpenAI

    GPT-5.4 is an advanced artificial intelligence model developed by OpenAI to support complex professional and technical work. The model combines improvements in reasoning, coding, and agent-based workflows into a single system designed for real-world productivity tasks. GPT-5.4 can generate, analyze, and edit documents, spreadsheets, presentations, and other work outputs with greater accuracy and efficiency. It also features improved tool integration, enabling the model to interact with software environments and external tools to complete multi-step workflows. With enhanced context capabilities supporting up to one million tokens, GPT-5.4 can process and reason over very large amounts of information. The model also improves factual accuracy and reduces errors compared to earlier versions. By combining strong reasoning, coding ability, and tool use, GPT-5.4 helps users complete complex tasks faster and with fewer iterations.
  • 26
    Grok 4.3
    Grok 4.3 is the latest iteration of xAI’s Grok model, designed to deliver improved reasoning, real-time information access, and advanced task automation. It builds on earlier Grok 4 models by enhancing performance in complex problem-solving, coding, and analytical workflows. The model is integrated with real-time web and X (formerly Twitter) data, allowing it to provide up-to-date insights and answers. Grok 4.3 supports multimodal capabilities, enabling it to work with text, images, and other data types. It operates within the SuperGrok Heavy tier, offering access to more powerful compute and advanced features. The model is designed to handle long-context tasks and multi-step reasoning with greater accuracy. It also supports tool use and integrations, enabling it to interact with external systems and automate workflows. Overall, Grok 4.3 is positioned as a high-performance AI assistant for real-time, data-driven tasks.
  • 27
    OpenAI o3-mini-high
    The o3-mini-high model from OpenAI advances AI reasoning by refining deep problem-solving in coding, mathematics, and complex tasks. It features adaptive thinking time with adjustable reasoning modes (low, medium, high) to optimize performance based on task complexity. Outperforming the o1 series by 200 Elo points on Codeforces, it delivers high efficiency at a lower cost while maintaining speed and accuracy. As part of the o3 family, it pushes AI problem-solving boundaries while remaining accessible, offering a free tier and expanded limits for Plus subscribers.
  • 28
    ERNIE X1.1
    ERNIE X1.1 is Baidu’s upgraded reasoning model that delivers major improvements over its predecessor. It achieves 34.8% higher factual accuracy, 12.5% better instruction following, and 9.6% stronger agentic capabilities compared to ERNIE X1. In benchmark testing, it surpasses DeepSeek R1-0528 and performs on par with GPT-5 and Gemini 2.5 Pro. Built on the foundation of ERNIE 4.5, it has been enhanced with extensive mid-training and post-training, including reinforcement learning. The model is available through ERNIE Bot, the Wenxiaoyan app, and Baidu’s Qianfan MaaS platform via API. These upgrades are designed to reduce hallucinations, improve reliability, and strengthen real-world AI task performance.
  • 29
    Grok 4.20
    Grok 4.20 is an advanced artificial intelligence model developed by xAI to elevate reasoning and natural language understanding. Built on the high-performance Colossus supercomputer, it is engineered for speed, scale, and accuracy. Grok 4.20 processes multimodal inputs such as text and images, with video support planned for future releases. The model excels in scientific, technical, and linguistic tasks, delivering highly precise and context-aware responses. Its architecture supports deep reasoning and sophisticated problem-solving capabilities. Enhanced moderation improves output reliability and reduces bias compared to earlier versions. Overall, Grok 4.20 represents a significant step toward more human-like AI reasoning and interpretation.
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